Accuracy of urine flow cytometry and urine test strip
2021-2-25 · The diagnostic accuracy and predictive values of UFCand urine test strip were compared with the referencestandard of bacterial culture. Combinations of tests withdiscrete results were linked by Boolean operators to testimprovementsin accuracy performances. Sensitivity,specificity, positive and negative predictive values werecalculated for representative cut-offs (selected based onpreviously published data for comparison and aroundoptimal cut-offs from receiver operator characteristic(ROC) curves). ROC curves and their respective areasunder the curves (AUC) were calculated in R 3.3.0 using the pROC package to determine discrimina-tive power and optimal, unweighted cut-offs. Analyseswere stratified according to sex and hospital divisions.Calculated optimal cut-offs from ROC curves were usedto derive a diagnostic algorithm to predict relevant bac-teriuria. To estimate the robustness of the developed al-gorithm, the diagnostic accuracy of the selected cut-offswere calculated in a repeated 10-fold-split (of equal size)cross validation approach of the whole dataset using thecaret package, with …
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